Endocrine Abstracts

Introduction: Both endothelial dysfunction and albuminuria have been shown to be related to cardiovascular risk. We aimed to investigate relations between endothelial dysfunction, albuminuria and frequency of the microvascular complication in type 2 diabetic patients.Method: Forty type 2 diabetic patients (24 microalbuminuria and 16 macroalbuminuria) with a mean age of 57.2±10.8 years and 25 healthy control subjects with a mean age of 54.1±9.6 ...

Background and aims: Growth hormone and insulin-like growth factors to be involved in the pathogenesis of diabetic kidney disease. The aim of this study was ultrastructural evaluation of octreotide acetate on kidney tissue in streptozotocin (STZ) induced diabetic rats.Material and methods: Twenty-four male Spraque–Dawley rats divided into 3 groups; control (C), diabetic (D) and diabetic with octreotide aceatate (DO). The all diabetic rats were treat...

Introduction: Primary pituitary sarcoma causally unrelated to radiotherapy, but an increased risk of second brain tumors continues beyond 20 and 30 year after treatment.We report an acromegalic patient with intrasellar giant adenoma invased suprasellar and nasal cavity during follow-up after radiotherapy.Case: A 39-year-old woman had transsphenoidal and transcranial operation in 2002 and 2003 respectively. She had also conventional...

Introduction: SGLT2 inhibitors have been an important step in the treatment of diabetes. With numerous controlled experimental studies of these antidiabetic drugs, evaluation of real-life data after entry into clinical practice is an important condition. In our study, it was aimed to evaluate short-term results on glycemic control and weight loss in a narrow group of patients in the single tertiary medical center.Methods: The study was retrospectively de...

Introduction: Diabetes Mellitus is a significant metabolic condition characterized by its widespread occurrence and associated complications. Reports indicate that DM impacts 25% of the global population. The way individuals handle their existing illnesses throughout their lifetimes is crucial in terms of uncertainty and self-care behaviors within chronic diseases such as DM. The connection between individuals’ physiological parameters (HbA1c etc.) and uncertainty, as wel...

Introduction: Polycystic ovary syndrome (PCOS) stands out as one of the prevalent endocrine disorders affecting women in their reproductive years, impacting 8-13% of females as per World Health Organization (WHO) statistics. This condition has significant repercussions on a woman’s sense of self, mental well-being, and overall life quality. While individuals with PCOS often grapple with anxiety and sadness throughout the diagnosis and treatment phases, external factors ca...

Objective: The measurement of epicardial adipose tissue (EAT) sonographically is reported to be related with both obesity and insulin resistance. Hepatic steatosis is one of the best known other coincidence with obesity. We aimed to evaluate the relationships between EAT thickness, hepatic steatosis and insulin resistance in obese patients.Methods: Obese 63 subjects were enrolled into the study. Local ethical committee approval was obtained. Patients wer...

Background: Various molecular mechanisms play a role in the pathogenesis of papillary thyroid cancer(PTC). Understanding the underlying pathogenesis and genetic changes is needed to improve clinical outcomes in PTC. In this study, it was aimed to determine the frequency of, BRAF V600E TERT promoter and NRAS mutations in Turkish patients with papillary thyroid cancer, the relationship of mutations between clinicopathological features and distant met...

Objective: Ultrasonographic (US) echogenic micro-foci are frequently seen in papillary thyroid carcinoma (PTC). General belief is that microcalcifications represent psammoma bodies. But the subject is debatable and other sonographic intranodular echogenic figures can be seen in PTC. We aimed to examine the nonshadowing echogenic figures and their histopathological correlations in PTC.Methods: We prospectively collected US video records of PTC cases with ...

Objective: Primary hyperparathyroidism (PHP) is a common endocrine disorder diagnosed biochemically, common use of autoanalyzers increased the incidence of PHP throughout last decades. Minimally invasive parathyroidectomy has been preferred to the explorative surgical approach due to shorter operating time, lower complication rate, and smaller incision size. Thus localization studies have become very important. We aimed to investigate clinical and laboratory characteristics of...